Charlie Murphy, comedian and brother to Eddie Murphy, died on Wednesday morning following a battle with leukemia, TMZ reports. He was 57.

Charlie’s manager confirmed the news to TMZ, noting that the he had been undergoing chemotherapy. He died in a New York City hospital.

Charlie, like his brother, made a name for himself in the comedy world. One of his famous appearances was in a skit on “Chappelle’s Show,” about the night he partied with Prince. Many of his sketches on the show were among its most memorable.